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[DOI] [PubMed] [Google Scholar] Berk M, Dean O, Cotton SM, Gama CS, Kapczinski F, Fernandes BS, Kohlmann K, Jeavons S, Hewitt K, Allwang C, Cobb H, Bush AI, Schapkaitz I, Dodd S, Malhi GS

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Similarly, in GPx1 −/− mice, deficiency of GPx1 increased ROS (as measured by DCF fluorescence of brain homogenates), lipid peroxidation, and protein carbonylation in brains exposed to the Aβ peptide, whereas forced overexpression of GPx1 in the GPx1 −/− mice attenuated these detrimental effects [124]